According to Cathy Goldstein, MD, MS, associate professor of neurology at the University of Michigan Sleep Disorders Center, data gathered during sleep examination and interpreted by AI could predict the onset of diseases even before the first appearance of symptoms.

Indeed, a polysomnography is complete and in-depth sleep examination allowing the recording of several variables (cardiac, cerebral, muscular, ocular, and respiratory activity) thanks to sensors and electrodes placed on the body. The interpretation of those big amount of data collected during a night of sleep by AI could predict who is going to get dementia in the future, thanks to specific patterns identified in the data.
For instance, observing a change in heart rate variability could signal the onset of pneumonia, which if identified upfront could be considered and prevented by treating physician.

Indeed, there’s already evidence that certain subtypes in obstructive sleep apnea (OSA) are predictive of cardiovascular events. But thanks to AI and its in-depth analysis, new important data could be identified allowing physician to select the right treatment for the right patient at the right time. As opposed to where we stand today, according to Alyssa Cairns, PhD, head of sleep research at SleepMed BioSerenity, with a data interpretation done by a sleep technician that looks at each 30-second window of the patient’s sleep, taking time and introducing human bias. Moreover, the sleep tec interpretation does not allow for an in-depth analysis as those that could be reach thanks to AI. Hence, why sleeps researchers and innovators are working actively on how polysomnography examination is interpreted, in order to improve sleep care and maybe care beyond sleep.

To know more, read the full article on Sleep Review: https://www.sleepreviewmag.com/sleep-diagnostics/connected-care/ai-machine-learning/artificial-intelligence-sleep-medicine-new-population-health-insights/

Bridging the healthcare gap: Building the case for epilepsy virtual clinics in the current healthcare environment.

In this article published in “Epilepsy & Behavior” journal, authors question themselves about access to healthcare: how can we facilitate access to quality care in a healthcare environment transformed by the pandemic? Difficulties in care continuity have emerged for patients suffering from serious chronic disorders, who usually require regular visits to their specialist.

To support a healthcare system greatly impacted by the pandemic, authors investigate virtual clinics and telehealth services to optimize care for these patients.

The article takes the situation of epileptic patients, who do not have enough specialist available close to their home. An absence that can be explained by the disease’s diagnostic test of reference, the electroencephalogram (EEG). A test that remains poorly recognized outside epilepsy. During this period, the lack of availability of specialists has also emerged as an issue.

These barriers to continued quality care can be overcomed by the introduction of virtual clinics. Clinics that would place the technologies directly in patients’ homes or at local clinics near the patients’ homes. This way, patients could benefit from specialists that provide quality care, anywhere in the world, at any time of the day.

19th of April, professor Hervé Vespignani, BioSerenity’s French medical director was interviewed on French live television and radio to talk about neurological consequences observed in COVID-19 patients. In the interview, the professor speaks about the recent discovery made by Neurophy’s team of EEG irregularities in some COVID-19 patients.

These abnormalities, which are characteristics of an encephalitis, show the virus’ impact the cerebral cortex through an inflammatory mechanism. The professor on the behalf of his team, warns the medical population, through these interviews and a coming publication, to stay alert for potential neurological manifestations in COVID-19 patients. He even recommends the systematization of EEG exploration for patients in reanimation that experienced a delay in waking-up from the induced coma, for the more severe patients that required respiratory support.

Indeed, this delay, if not explained by complications linked to the sedation could be explained by the inflammation. Hence the importance of performing an EEG as soon.

Herpes simplex encephalitis: A new type of “ICU-acquired infection”?

This is the question MDs Fabien Hauw, Nicolas Engrand, Vera Dinkelacker, Pierre Jaquet, Charles Gregoire, Mathilde Perrin, and MD-PhD Hervé Vespignani (Medical Director in France of Serenity Medical Services) have asked themselves in their recent experience with a patient received in ICU for a respiratory failure.

The patient, 87 of age, was received in the ICU following an exacerbation of his myasthenia gravis. One month after the successful treatment of his exacerbation, the patient, still hospitalized, developed fever and confusion. In the context of confounding factors, HSE (Herpes simplex encephalitis) was not suspected before a convulsive status epilepticus occurred, resulting in a significant delay in treatment. Diagnosis was confirmed by PCR-analysis in the cerebrospinal fluid and serological status confirmed reactivation of prior herpes simplex infection. Beside HSE treatment, the patient died one week after the onset of confusion.

The co-authors reporting this case want to highlight the challenging diagnosis of HSE during hospitalization which can be made even more difficult by nonspecific symptoms due to previous diseases. But also alert on the related diagnosis pitfalls, such as more severe prognosis in vulnerable patients. They conclude that hospital-“acquired” HSE must be suspected in case of new neurologic symptoms associated with fever, even in ICU-hospitalized patients.

BioSerenity and Serenity Medical Services attended the 30th European Days of the French Society of Cardiology held in Paris from January 15th to 18th, 2020.

Cardiophy is specialized in the performance and interpretation of resting electrocardiograms (ECG) and Holter ECG. Cardiophy’s objective is to ensure efficient patient care with optimal organizational flexibility. Cardiophy provides continuity of care in synergy with local teams and medical specialists. In addition, Cardiophy provides access to medical innovation through a secure digital platform, connected medical devices, and a paramedical team to help patients throughout all the ECG recording.

Nice, december 4th 2019 – BioSerenity and its medical subsidiary company attended the French Congress of Psychiatry in Nice, between the 4th and 7th december 2019.

During this event, the interest of alectrophysiology in psychiatry was highlighted during a workshop moderated by Prof. Schwan (Nancy) in presense of Dr. Micoulaud-Franchi (Bordeaux), Pr. Vespignani (Nancy ) and Dr. Schwitzer (Nancy). In particular, during this conference, the importance of electrophysiological monitoring (EEG, PSG and ERG) in psychiatry was emphasized.

More particularly, according to the speakers, the evaluation of the EEG as part of the patient journey in psychiatry should be used as a bioelectric marker of pathologies treatable by non-psychiatric therapeutics, but also as a bioelectric marker of the response and tolerance to treatments, particularly in narrow margin specialized therapies. In addition, EEG could be used as a bioelectric marker in a psychophysiological perspective to consider personalized neuro-modulatory therapies.

Also, psychiatric comorbidities and sleep have been highlighted as well as the importance of investigating the patients’ sleep quality in a systematic way in the care pathways in psychiatry.

Finally, the ERG was recognized by stakeholders as a tool for evaluation and prediction of the response to psychiatric treatment and its use could be relevent in clinical practice for the differential diagnosis between unipolar depression and bipolar depression.

Nancy, November 20th 2019 – The Nancy-Barbois Regional University Hospital Center opens an economic research project center focused on healthcare, within the Health Research and Innovation Institute.

In this space dedicated to hosting startups, companies under a research agreement with the Regional University Hospital Center, and reaseachers developing innovations, BioSerenity is proud to be part of the first startups opening a new branch in the Technopôle Henri-Poincaré.

For more information please consult our press release.

Metz (France) – 27 October 2019

On Friday 27^th and Saturday 28^th of October, the second edition of GETCOP congress (Evaluation Group of Personalized Complementary Therapies) took place in Metz. This year’s theme was “sleep disorders and personalized complementary therapies”.

For this occasion, several sleep specialists have been met to discuss and exchange about new technics and complementary therapies for a better sleep. Among them, Professor Hervé Vespignani, medical director of Serenity Medical Services and national coordinator of CEREVES sleep centers, was present as a member of the scientific committee.

Find the professor Vespignani’s interview on TV news France 3 Lorraine.

Nancy – 19 June 2019 – Serenity Medical Services, committed to bringing practical solutions to specialists in neurology and sleep disorders, attended the 4th Days of Clinical Neurophysiology.

Available 24/7, Neurophy teams are composed by EEG technicians and medical interpreters, neurologists, specialized in EEG from premature infants to adults.

Our CEREVES sleep centers welcome patients from sunday to saturday for a complete care of their sleep disorders, on prescription.

Paris (France) – 22 March 2019 – At the time of the digital revolution, the impact of lifestyles on our sleep is one of the major questions of people with sleep disorders. On the occasion of the 19th French Sleep Day, CEREVES centers opened theirs doors, in partnership with the National Institute of Sleep and Vigilance.

At Epinal, Nancy, and Thionville, over a hundred visitors were received by the local teams to visit the centers and attend conferences given by each physician Head of department.

To better understand the impact of lifestyle on sleep, find the results of the INSV survey on : www.villagesommeil.org

Your local CEREVES center in a clic :

• Epinal
• Nancy
• Paris
• Thionville